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Biomechanics Forum

COEFFICIENT OF FEMALE PELVIS

Submitted by cinzia on

Hello all!

I am an italian student at the University of Florence....

For my thesis I need to know some coefficient for the female pelvis....like Poisson Ratio,Young Module and Density of uterus, urinary bladder,pelvic bone and rectum.

Someone can help me?Where I can find them?Or someone knows them??

Thank you very much.

cinzia

orthopedical implant production method

Submitted by Anonymous (not verified) on

Hello,

I would like to learn the most suitable way to produce a titanium implate plate (with press, milling machine, cnc...)

The picture of the material that i would like to produce is attached,

if anyone should advice me about that, i will be so grateful.

best wishes,

adem atmaca

An overview of bio-mechanical models for bones and related topics

Submitted by Evgeny Savenkov on

Hi everyone!

I'm looking for a good comprehencive overview about bio-mechanics and numerical simulation in

bio-mechanics. I'm mainly interested in the following topics:

-- mathematical models for bone simulation

-- contact problems and corresponding models (e.g., bone-prosthesis models, etc.)

-- corresponding numerics/simulations

and corresponding state-of-the-art.

Thanks in advance! 

 

clever load normalization parameters for hip joint prosthesis

Submitted by Mike Ciavarella on
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A normalising loading parameter useful in summarising the mechanical response of plane, pin in plate-like contacts is extended to axisymmetric, ball in socket-like contacts. Various diagrams reporting

Critical role of cytoskeletal prestress in cellular stiffening

Submitted by Ning Wang on

In his recent comment, Isabey discussed the issue of external stress/strain induced cellular stiffening. While the mechanism of this behavior is not fully understood and deserves further investigation, I would like to mention the cellular stiffening (increase of shear stiffness) that depends on the level of the endogenous contractile prestress (pre-tension) generated by myosin II-actin interactions.

Nonlinear elasticity of biological gels

Submitted by Kilho Eom on
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I would like to propose the recent papers by Janmey, P.A., and coworkers on the nonlinear elasticity behavior of biopolymer gels for "biomechanics" issue in J Club. In their original work, they proposed the biopolymer network model composed of semi-flexible polymers that behave like a worm-like-chain (WLC) model. Their models surprisingly capture the mechanical response of biopolymer gels such as neuro-filaments. The details of their work are as follows:

Post-doctoral positions in personalized cardiac electro mechanics

Submitted by afrangi on
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Post-doctoral positions in personalized cardiac electro mechanics

Pompeu Fabra University - Barcelona – Spain

 The Computational Imaging Lab (www.cilab.upf.edu) at the Pompeu Fabra University in Barcelona is a team focused on algorithmic and applied research in the area of computational imaging, modelling and simulation. The lab is composed of 25 members working in different domains of medical image segmentation, statistical shape modelling and analysis, computational geometry, pattern recognition and image-based and personalised computational mechanics.Currently, the lab is engaged in several exciting projects aiming at personalised physical modelling and simulation in the cardiovascular domain where medical imaging, computational mechanics, and biology play an essential role. This post is connected to a national technology platform funded by the Ministry of Industry that aims at applying computational imaging and simulation technologies to patient selection and interventional planning in cardiac resynchronization therapy. Our aim is to develop dynamic anatomical models of the whole heart as well as to derive boundary conditions and material properties from multimodal imagery (e.g. 3D US, MRI, MSCT, SPECT). Integration of all this information will be performed by combination of computational imaging tools with computational mechanics in order to deliver advanced diagnosis and personalized treatment planning and optimization.   The CILab is seeking proactive and highly talented post-doctoral researchers with proven track record of publications in leading international journals and conferences. Candidates should be highly creative, have the ability to carry out independent research but work embedded in a multicultural research team, and should be endowed with excellent communication and leadership skills so as to collaborate with other peers. The ability to work in a multidisciplinary team and be able to interact with other disciplines is essential. All applicants should have a strong background in mathematics and physics, algorithmics and programming [preferably in C++]. Proficiency in spoken and written English is compulsory. Candidates with should have expertise in computational cardiac modelling and simulation, in particular, on cardiac electrophysiology, cardiac mechanics, and computational fluid dynamics. The main focus of the research will be in the integration of the existing tools in the lab for computational imaging with computational physiology models and experimental measurements. The candidate will have to interact with members of the lab of related topics as well as with our clinical collaborators at several academic hospitals in Barcelona. 

Starting dates will be prior to May 2007; positions will be for a period of 3 years. Salaries are negotiable depending upon qualifications and experience of the applicants and compliant with Spanish salaries in academic institutions. EU citizens will be given priority due to labour regulations and work permit constraints.

Mechanism of mechanotransduction

Submitted by Ning Wang on

Recent comments by AA Spector are interesting and deserve further discussion. Earlier elegant work by Maniotis and Ingber demonstrated the interconnectedness between the cell surface (via integrins) and the nucleus through the cytoskeleton. Coffey also promoted the importance of cytoskeleton in mechanical signal transduction in normal cells and the differences in tumor cells. There ideas are not well received, however, by the field. An important issue is the magnitude of the surface deformation: if it is large, then one expects the nucleus to be deformed. A finite element analysis by SM Mijailovich et al (J Appl Physiol, 2003) showed that a localized surface load decays rapidly in space-as a function of distance squared, suggesting that a physiologic load may not be able to deform structures inside the nucleus directly. This is consistent with St Venant principle that states a local force causes only a local deformation. A recent review by Vogel and Sheetz also highlighted the importance of local deformation leading to local biochemical activities.