Many researchers and engineers view mechanical fatigue of metals as a stagnated field, evidenced by the lack of substantially novel design approaches against fatigue in recent decades. However, our current capability to investigate, probe, and model the multiscale mechanisms of fatigue damaging processes may turn out to be pivotal for next-generation paradigms for the assessment of fatigue.
The classical continuum mechanics assumes that a material is a composition of an infinite number of particles each of which is a point that can only move and interact with its nearest neighbors. This classical mechanics has limited applications where it fails to describe the discrete structure of the material or to reveal many of the microscopic phenomena, e.g., micro-deformation and micro-dislocation.
https://doi.org/10.1016/j.coche.2019.02.011 We review the most recent developments in multiscale computational modeling of collagen-based biomaterials to determine their structural, mechanical, and physicochemical properties. Through the materials-by-design paradigm, these developments may eventually lead to rational algorithmic recipes for bottom–up multiscale design of these biomaterials, thereby minimizing the experimental costs of iterative material synthesis and testing.
https://doi.org/10.1002/mabi.201800253 In celebration of Stern Family Professor of Engineering David L. Kaplan, on the occasion of his 65th birthday, we review a selection of relevant contributions of computational modeling to understand the properties of natural silk, and to the design of silk-based materials, especially combined with experimental methods.
Peipei Li Derek Warner Ali Fatemi Nam Phan
Nanomechanical Resonators and Their Applications in Biological/Chemical Detection: Nanomechanics Principles
Kilho Eom, Harold S. Park, Dae Sung Yoon, Taeyun Kwon
Abstract
dear iMechanica friends
I came across a review of a paper by HD Bui who was somewhere in the internet, and I find it is very interesting. I could even have written this review myself !! I don't think the reviewer exaggerates....
michele
There has been a lot of attention on the study of mechanics of proteins and/or single molecules. Such study was typically implemented by using classical molecular dynamics (MD) simulation. In spite of ability to describe the dynamics of biological macromolecules (e.g. proteins), MD simulation exhibits the computational restriction in the spatial and temporal scale. In order to overcome such computational limitation, the coarse-grained model has recently been taken into account. In this review, I would take a look at a couple of coarse-grained models of protein molecules.
