User login


You are here

Nanoindentation of Biological Materials

MichelleLOyen's picture

Recently published, this special issue of the Journal of the Mechanical Behavior of Biomedical Materials, dedicated to ‘Nanoindentation of Biological Materials' provides a snapshot of the novel uses on nanoindentation technology that is now readily available to researchers and expands the scope of existing techniques to optimize methods for biological tissues and related biomaterials.
Access the issue online: (ScienceDirect subscribers) (Non-subscribers)

Journal of the Mechanical Behaviour of Biomedical Materials
Volume 2, Issue 4, Pages 311-408
Nanoindentation of Biological Materials - Edited by Michelle Oyen and David Taylor

1. Surface detection errors cause overestimation of the modulus in nanoindentation on soft materials, Jessica D. Kaufman, Catherine M. Klapperich
2. Determination of viscoelastic-plastic material parameters of biomaterials by instrumented indentation, Jaroslav Menčík, Li Hong He, Michael V. Swain
3. A fiber reinforced poroelastic model of nanoindentation of porcine costal cartilage: A combined experimental and finite element approach, Shikha Gupta, Jeremy Lin, Paul Ashby, Lisa Pruitt
4. Nanoindentation of the insertional zones of human meniscal attachments into underlying bone, K.N. Hauch, M.L. Oyen, G.M. Odegard, T.L. Haut Donahue
5. Effect of osteocalcin deficiency on the nanomechanics and chemistry of mouse bones, N.B. Kavukcuoglu, P. Patterson-Buckendahl, A.B. Mann
6. Mechanical characterization of soft viscoelastic gels via indentation and optimization-based inverse finite element analysis, Kaifeng Liu, Mark R. VanLandingham, Timothy C. Ovaert
7. Deformation partitioning provides insight into elastic, plastic, and viscous contributions to bone material behavior, V.L. Ferguson
8. Use of focused ion beam milling for investigating the mechanical properties of biological tissues: A study of human primary molars, Y.L. Chan, A.H.W. Ngan, N.M. King
9. Indentation techniques for evaluating the fracture toughness of biomaterials and hard tissues, J.J. Kruzic, D.K. Kim, K.J. Koester, R.O. Ritchie
10. A practical guide for analysis of nanoindentation data, Michelle L. Oyen, Robert F. Cook


Hello Michelle,

Thanks for the nice review. Has someone used nanoindentation techniques under high temperatures or under high pressures? Are there any off-the-shelf equipment that can operate under pressures of 500-900 bar and temperatures up to 120°C?

My idea is to investigate particular phases of multiphase polymeric material. These phases occure at high pressures and temperatures.



Yuhang Hu's picture

Hellow Michelle,


Actually I have the same question as Almir.

Do you know how temperature affects the experimental results in indentation testing?

Thank you very much!

Subscribe to Comments for "Nanoindentation of Biological Materials"

Recent comments

More comments


Subscribe to Syndicate