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Alport syndrome

Jingjie Yeo's picture

Adverse effects of Alport syndrome-related Gly missense mutations on collagen type IV: Insights from molecular simulations and experiments Our unified experimental and computational approach provided underlying insights needed to guide potential therapies for Alport syndrome (AS) that ameliorate the adverse effects from AS disease onset and progression. Patients with AS exhibit blood and elevated protein levels in their urine, inflamed kidneys, and many other abnormalities.

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