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Intracellular CalciumWaves in Bone Cell Networks Under Single Cell Nanoindentation

Submitted by Ed Guo on

In this study, bone cells were successfully cultured into a micropatterned network with dimensions close to that of in vivo osteocyte networks using microcontact printing and self-assembled monolyers (SAMs). The optimal geometric parameters for the formation of these networks were determined in terms of circle diameters and line widths. Bone cells patterned in these networks were also able to form gap junctions with each other, shown by immunofluorescent staining for the gap junction protein connexin 43, as well as the transfer of gap-junction permeable calcein-AM dye.

CFRAC 2007 International Conference on Computational Fracture and Failure of Materials and Structures

Submitted by Nicolas MOES on

If you are interested by the computational aspects of fracture and failure of materials and structures,there is a dedicated conference for you : CFRAC 2007, which will be held in Nantes, France, 11-13 June 2007. It is an thematic conference of the European Community in Computational Methods in Applied Sciences (ECCOMAS). The for abstract is now closed. This conference wil involve a certian number

No need to worry about gravity at the atomic-/nano-scale

Submitted by Zhenyu Zhang on

When a metal is grown onto a substrate of itself (homoepitaxy), the growth front is typically smooth, or at most is roughened by the formation of shallow hills (called surface mounds). The underlying reason for the roughening has been recognized to be of kinetic nature: Atoms landed on an upper terrace do not have enough time to overcome the "road blocks" provided by the steps and fill all the valleys (known as the Villian instability).

Operating Notes for the iMechanica Journal Club

Submitted by Managers on
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Guided by a thread that proposed the Journal Club, we evolve these operating notes. These notes are a work in progress, and will evolve as the iMechanica community and the Web technology evolve. Every moderator and architect can edit these notes. Every user can see the editing history. As always, every registered user can make suggestions by leaving comments.