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Postdoc Position in Microstructural Analysis for Tissue Diagnostics Available at Heriot-Watt University (Edinburgh, UK)

2.5 years postdoc position in tissue microstructural modelling available immediately at Heriot-Watt University.

For more information about this post, please go to Link or contact me directly at  y.chen AT


The consortium of 4 UK Universities (Heriot-Watt, Liverpool, Edinburgh and Durham) was recently awarded a major research grant by the EPSRC to undertake a multidisciplinary project entitled "A novel diagnostic tool: from structural health monitoring to tissue quality prediction". The project aims to evaluate the tissue quality using: advanced and novel high resolution imaging technologies; microstructural analysis; nonlinear modelling and homogenisation; and tissue biomechanical characterisation. The project will bring together scientists and clinicians in a multi-disciplinary effort to design a computational tool using new microstructural indices found for early diagnosis of microstructure-related disease at tissue level.

This advertisement is for the PDRA post based at the School of Engineering and Physical Sciences, Heriot-Watt University. The post-holder will be working with other members of computational bioengineering group led by Dr. Yuhang Chen. The post-holder will be expected to communicate regularly within the consortium, attend and present research findings at internal project meetings and international conferences. They will also contribute to the internal and external visibility of the research groups and publish scientific results arising from this project.

The PDRA will be responsible for developing novel mathematical/numerical methods to quantitatively assess the tissue quality using high-resolution microstructural images from various imaging techniques. Although bone tissue was originally proposed as an exemplar for the project, studies on soft tissue may also be carried out to understand the relationship between tissue mechanical behaviour and microstructural hierarchy. Main work will involve tissue microstructural analysis under different physiological conditions; linear/nonlinear finite element modelling; tissue hierarchy and heterogeneity at different length scales; and modelling of tissue biomechanical/biochemical micro-environment. The post-holder will also work closely with the project team consisting of other investigators, PDRAs and clinical advisors.

The candidate will have a PhD (or nearly-finished) in mechanical engineering, biomedical engineering, physics or closely related field and a proven research track record in computational mechanics and/or tissue mechanics. Sound experience in programming in one or more of the following languages is desired: Fortran, Matlab, Python, C++, APDL etc. A research background in more than one of the following subjects is a plus: biomedical imaging; orthopaedic biomechanics; tissue microstructural analysis; mechanobiology; homogenisation methods; and modelling anisotropic materials.

Interested candidate should send C.V. and relevant documents to Dr. Yuhang Chen (y.chen AT, no later than 7/Nov/2013.

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