Partial- and
full-thickness cartilage lesions of the knee caused by trauma, disease or joint
instability are a common disorder affecting people of all ages. Implanted
cartilage replacements (ICR) have the potential to overcome the limitations of
conventional treatment methods and are a promising approach to restore
functionality of the joint. In spite of some success in engineering
cartilaginous tissue, inferior biomechanical and biochemical properties of ICR
compared to native articular cartilage (AC) and inadequate quality of fixation
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