In order to achieve a wide variety of biological phenomena, the abilities of cells to contact effectively and interact specifically with neighboring media play a central role. It is known that cells can sense the chemical and mechanical properties of surrounding systems and regulate their adhesion and movement through binding protein molecules within cell membrane. The kinetics of binding molecules interacting with ligands is of great interest in biophysical society. There are lots of discussions and contributions on cell mechanics from our mechanical society, e.g.